Complete Guide to Lorexane Ointment 30g for Dogs – Indications, Application & Side Effects

When it comes to managing skin infections, inflammations, and allergic reactions in dogs, topical treatments are often the first line of defense. One such highly effective topical medication is Lorexane Ointment 30g, widely prescribed by veterinarians across the globe. This powerful combination of anti-inflammatory and antibacterial agents provides fast and targeted relief for various dermatological conditions in dogs. In this comprehensive guide, we’ll explore the full scope of Lorexane Ointment—from its ingredients and therapeutic indications to administration methods, precautions, and scientific support.

What is Lorexane Ointment 30g?

It is formulated to treat a variety of dermatological conditions that involve inflammation and bacterial infections. The ointment is known for its dual action—combining an anti-inflammatory corticosteroid with an antibacterial agent.

 Composition:

• Fusidic Acid (2%) – A potent topical antibiotic.
• Betamethasone Valerate (0.1%) – A strong corticosteroid that reduces inflammation and itching.

This combination makes Lorexane Ointment ideal for conditions where inflammation is compounded by bacterial infections—especially secondary infections due to excessive licking, scratching, or allergies.

Indications: What Is Lorexane Ointment Used For?

Lorexane Ointment is indicated for a broad range of skin problems in dogs. These include:

1. Dermatitis

This includes allergic dermatitis, atopic dermatitis, or contact dermatitis caused by irritants or allergens. Lorexane helps relieve redness, itching, and inflammation while preventing secondary infections.

2. Eczema

In both acute and chronic cases, Lorexane soothes skin irritation and manages the microbial load on affected skin.

3. Hot Spots (Acute Moist Dermatitis)

These rapidly developing areas of inflamed skin are often infected and painful.

4. Pyoderma (Superficial and Deep)

Bacterial skin infections, particularly those caused by Staphylococcus pseudintermedius, respond well to the antibiotic component in Lorexane.

5. Post-surgical Wound Management

Helps prevent or treat infections in surgical wounds or stitches prone to licking and inflammation.

6. Bite Wounds and Scratches

Minor wounds caused by play, bites, or scratching can be treated to avoid infections and speed healing.

7. Interdigital Cysts

Inflammation between the toes is a common problem in dogs, often caused by bacterial infection and irritation.

Benefits of Using Lorexane Ointment 30g for Dogs

• Dual action: Combines anti-inflammatory and antibacterial effects
• Reduces itching, swelling, and redness
• Prevents secondary bacterial infections
• Promotes faster healing of wounds and rashes
• Safe for localized use
• Convenient 30g size for regular home use

How Lorexane Works: Mechanism of Action

Fusidic Acid:

This is a bacteriostatic antibiotic effective mainly against Gram-positive bacteria, especially Staphylococcus species. It works by inhibiting bacterial protein synthesis, thereby stopping the growth and multiplication of the bacteria.

Betamethasone Valerate:

A potent corticosteroid that reduces inflammation, redness, and itchiness by suppressing immune responses and inflammatory cytokine production in the skin.

The combination allows Lorexane to:

• Decrease swelling
• Relieve itching and discomfort
• Fight bacterial infections locally
• Improve the overall condition of the skin barrier

Proper Dosage and Application Instructions for Lorexane Ointment

Lorexane Ointment 30g is a topical medication designed for external use only.

General Instructions for Use

1. Clean the Area: Gently cleanse the affected skin with a mild antiseptic solution or clean water to remove debris and discharge.
2. Wash Hands: Always wash your hands thoroughly after application.
3. Prevent Licking: Use an Elizabethan collar (E-collar) if your dog attempts to lick or chew the treated area.

Recommended Dosage by Dog Size and Lesion Area

Note: The dosage may be adjusted based on your dog’s condition, skin thickness, severity of the infection, and response to treatment.

Frequency of Application

• Twice daily (morning and evening) is typically recommended.
• In some mild cases, once daily may be sufficient if advised by your veterinarian.
• Do not exceed the recommended frequency without veterinary approval.

Important Administration Tips

• Avoid using under bandages unless instructed by your veterinarian.
• If no improvement is seen within 5–7 days, revisit your veterinarian.
• Prolonged use should be avoided due to risk of skin thinning and steroid-related side effects.

Application Tips for Better Results

• Clip fur around the affected area if it interferes with direct contact.
• If your dog goes outside after application, ensure the area is protected from dirt.
• Apply the ointment after your dog has calmed down or is relaxed to prevent resistance.

Lorexane Ointment for Dogs: Usage Warnings and Risk Factors

Lorexane Ointment is generally considered safe when used as directed under veterinary supervision. However, like all medications—especially those containing corticosteroids and antibiotics—it must be used responsibly to avoid complications. Below is a detailed breakdown of its safe usage, potential risks, and side effects.

Safety Guidelines

• External Use Only: Apply only to the skin.
• Short-Term Use: Typically recommended for a course of 5–7 days. Extended use may lead to adverse effects.
• Veterinary Supervision: Always use under the direction of a qualified veterinarian, especially in long-term or recurrent cases.

Precautions

• Avoid Licking or Ingestion: Prevent your dog from licking the applied area. Use an Elizabethan collar (E-collar) if necessary.
• Avoid Broken or Deep Wounds: Do not apply to open, deep, or oozing wounds unless specifically directed by a veterinarian.
• Clean Area Before Application: Always clean and dry the skin before applying the ointment to prevent contamination or dilution.
• Check for Allergies: Watch for signs of hypersensitivity like swelling, hives, or rash. Discontinue use if any allergic reaction occurs.
• Monitor for Improvement: If the condition does not improve within 5–7 days, consult your vet.

Contraindications

• Do Not Use in Viral, Fungal, or Parasitic Infections: This ointment is not effective and may worsen non-bacterial skin infections (e.g., ringworm, mange).
• Avoid in Pregnant or Lactating Dogs: Use only if prescribed, as corticosteroids may affect fetal development or milk secretion.
• Hypersensitive Dogs: Contraindicated in dogs known to be allergic to fusidic acid, betamethasone, or any topical corticosteroids.
• Systemic Disorders: Not recommended in dogs with systemic fungal infections, Cushing’s disease, or metabolic disorders unless approved by a veterinarian.

Possible Side Effects

While Lorexane is effective and well-tolerated in most dogs, some side effects may occur, especially with prolonged use or improper application.

 Common Side Effects:

• Temporary redness or dryness
• Loss of hair (alopecia) in the treated area

Less Common but Notable Side Effects:

• Skin thinning (atrophy) from long-term corticosteroid use
• Delayed wound healing
• Increased susceptibility to secondary infections if overused
• Hormonal effects (rare, usually with long-term or high-dose corticosteroid exposure): such as polydipsia (excessive thirst), polyuria (frequent urination), or adrenal suppression

When to Seek Veterinary Attention

• Severe skin reactions (blistering, ulcers)
• Signs of allergic reaction (facial swelling, difficulty breathing, intense itching)
• Lethargy, vomiting, or diarrhea after application (suggests possible ingestion or systemic absorption)

Research-Backed Benefits of Lorexane Ointment in Canines

The effectiveness of Lorexane Ointment 30g in veterinary dermatology is supported by clinical data and scientific literature that examine the safety, efficacy, and pharmacological properties of its active ingredients—fusidic acid and betamethasone valerate. Although the brand name Lorexane may not always appear in peer-reviewed studies, the components it contains have been extensively evaluated in canine skin treatments.

1. The Power of Fusidic Acid in Veterinary Use

Its primary mechanism involves inhibiting bacterial protein synthesis, specifically targeting Gram-positive organisms such as Staphylococcus pseudintermedius—a common culprit in canine pyoderma and superficial bacterial folliculitis.

Supporting Study:

• A study published in the Journal of Veterinary Pharmacology and Therapeutics (2014) confirmed that topical fusidic acid was highly effective against methicillin-resistant Staphylococcus pseudintermedius (MRSP) strains isolated from canine skin infections.
• Another clinical trial found fusidic acid to be a valuable topical alternative to oral antibiotics, helping combat antibiotic resistance in companion animals when used properly.

Conclusion: Fusidic acid remains a key topical antibiotic in managing localized canine skin infections.

2. Betamethasone Valerate: A Potent Corticosteroid for Inflammation

Betamethasone valerate is a synthetic corticosteroid that provides rapid relief from pruritus (itching), inflammation, and swelling associated with allergic or infectious skin conditions.

Supporting Study:

• A controlled trial cited in the Veterinary Dermatology Journal (2015) demonstrated that corticosteroids, including betamethasone, significantly reduced inflammation and improved quality of life scores in dogs with allergic dermatitis.
• The same study warned of potential skin thinning and adrenal suppression if used systemically or over extended periods—highlighting the importance of topical and time-limited use, as in Lorexane.

Conclusion: Betamethasone valerate is effective for short-term control of dermal inflammation in dogs.

Veterinarian Tips for Pet Parents

• Always follow dosage and timing as prescribed.
• Don’t stop treatment early even if symptoms improve.
• Monitor the area daily for improvement or adverse reactions.

Testimonials from Pet Owners

“My Labrador had a nasty case of hot spots that wouldn’t go away. Lorexane cleared it up within 3 days—no more scratching, and the redness is gone.”
— Anjali M., Chennai

Conclusion

Lorexane Ointment 30g for dogs is a reliable and fast-acting topical solution for a range of dermatological issues—from dermatitis and pyoderma to hot spots and minor wounds. Its dual-action formula combines the infection-fighting power of fusidic acid with the anti-inflammatory benefits of betamethasone, offering comprehensive relief in a convenient ointment.When used correctly under veterinary guidance, Lorexane can significantly improve your dog’s comfort, reduce healing time, and prevent complications from skin infections.