Levothyroxine Sodium Tablets 25 mcg for Dog
Levothyroxine Sodium Tablets 25 mg are a veterinary thyroid hormone replacement used to manage hypothyroidism in dogs. This medication restores deficient thyroid hormone (T4) levels, helping normalize metabolism, energy, weight, and skin health.
What Levothyroxine Is Used For in Dogs
Levothyroxine is prescribed when a dog’s thyroid gland does not produce enough thyroxine (T4).
Primary indication:
- Canine hypothyroidism
Common symptoms it helps correct:
- Lethargy and low energy
- Unexplained weight gain
- Hair loss, dull or thinning coat
- Dry or flaky skin
- Cold intolerance
- Recurrent skin or ear infections
- Behavioral dullness or depression
How Levothyroxine Works
Levothyroxine Sodium is a synthetic form of thyroxine (T4).
Action in the body:
- Replaces deficient thyroid hormone
- Normalizes metabolic rate
- Supports energy production
- Improves skin, coat, and immune function
- Restores normal hormone balance
After absorption, T4 is converted to T3 (active hormone) in body tissues.
Key Benefits
- Restores normal thyroid hormone levels
- Improves energy and activity
- Supports healthy skin and coat regrowth
- Helps manage weight
- Reduces recurrent skin and ear issues
- Long-term control of hypothyroidism
Dosage & Administration
Form: Oral tablet
Strength: 25 mg
Route: Oral
Frequency: Usually twice daily
General veterinary dosing:
- 0.02–0.05 mg per kg body weight per day
- Divided into two doses
Administration guidelines:
- Give on an empty stomach (30 minutes before food)
- Administer at the same times daily
- Tablets should be swallowed whole
Dosage is adjusted based on blood thyroid levels.
Monitoring & Long-Term Use
Hypothyroidism treatment is lifelong.
Veterinary monitoring includes:
- Serum T4 testing (4–8 weeks after starting or dose change)
- Periodic rechecks once stabilized
Dose adjustments are common and expected.
Safety & Side Effects
Levothyroxine is generally safe when correctly dosed.
Possible side effects (usually from overdose):
- Increased thirst or urination
- Increased appetite
- Weight loss
- Restlessness or hyperactivity
- Rapid heart rate
Serious signs (seek veterinary care):
- Tremors or seizures
- Persistent panting
- Cardiac irregularities
Important Precautions
- Use with caution in dogs with heart disease
- Not interchangeable with human thyroid dosing
- Do not change dose without veterinary guidance
- Overdosing can cause hyperthyroidism
Drug Interactions
Inform your veterinarian if your dog is taking:
- Antacids
- Calcium or iron supplements
- Corticosteroids
- Certain seizure medications
These may affect absorption or effectiveness.
Storage Instructions
Store in a cool, dry place below 25°C.
Keep tightly closed and out of reach of pets and children.
FAQ
What is levothyroxine used for in dogs?
It treats hypothyroidism by replacing deficient thyroid hormone.
Is levothyroxine a lifelong medication for dogs?
Yes. Most dogs require lifelong thyroid hormone replacement.
How long does levothyroxine take to work in dogs?
Energy improves in 1–2 weeks; skin and coat changes take longer.
Can levothyroxine be given with food?
Absorption is best on an empty stomach.
What happens if the dose is too high?
Signs of hyperthyroidism may occur and require dose reduction.







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