Complete Protection in One Tablet
Credelio Plus pairs lotilaner with milbemycin oxime. Lotilaner is a fast-acting isoxazoline that kills fleas and ticks through the dog’s bloodstream. Milbemycin oxime prevents heartworm disease and clears the three most common intestinal worms. The result is a single monthly tablet that replaces what would otherwise be two or three separate products.
Elanco introduced this combination to India recently, so it is still new to most pet owners here — but the lotilaner molecule has an established international safety record.
Parasites Covered
Fleas, ticks, heartworm (Dirofilaria immitis) prevention, roundworm, hookworm and whipworm.
Built for Small Dogs
Small dogs are often the hardest to medicate, and a tablet they will not swallow is a tablet that does not work. The Credelio Plus chew is deliberately compact and flavoured for voluntary acceptance. Give it with food — the milbemycin component absorbs considerably better on a full stomach.
Specifications
| Specification | Detail |
|---|---|
| Active ingredients | Lotilaner 112.5 mg + Milbemycin oxime 4.22 mg |
| Dog weight range | 2.8–5.5 kg |
| Pack size | 3 chewable tablets |
| Form | Flavoured chewable tablet |
| Dosing frequency | One tablet monthly |
| Species | Dogs only |
| Manufacturer | Elanco |
Dosage & Administration
One chewable tablet by mouth per month, given with food. Match the tablet strength to the dog’s current weight. Dose on the same date each month for uninterrupted cover. Test for existing heartworm infection before beginning heartworm prevention.
Dr. Moliya (DVM) to verify against the current pack insert before publication.
Safety Information & Warnings
- For dogs only. Do not give to cats.
- Give with food — absorption of milbemycin oxime is significantly reduced on an empty stomach.
- Test for existing heartworm infection before starting.
- Use with caution in dogs with a history of seizures.
- Refer to the product label and package insert for complete safety, storage and handling information.
Frequently Asked Questions
What is the difference between Credelio and Credelio Plus?
Credelio contains lotilaner alone and covers fleas and ticks. Credelio Plus adds milbemycin oxime, which extends cover to heartworm prevention and intestinal worms. Plus is the more complete option if you are not already using a separate wormer.
Does it need to be given with food?
Yes. The milbemycin oxime component absorbs far better when the dog has eaten. Giving it on an empty stomach can reduce how well the heartworm and worm protection works.
How quickly does it kill ticks?
Lotilaner begins killing ticks within hours. Ticks need to attach and begin feeding before the active ingredient reaches them, so you may still see attached ticks shortly after dosing — they die before most disease transmission occurs.
Is Credelio Plus new in India?
Yes. Elanco introduced this combination to the Indian market recently, which is why fewer local pet owners are familiar with it than with older products.
Can it be used alongside a separate dewormer?
There is usually no need, since it already covers roundworm, hookworm and whipworm. It does not cover tapeworm, so if tapeworm is diagnosed your veterinarian may add a praziquantel product.
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