What is Unizif Plus Bolus for Horses?
Unizif Plus Bolus is a veterinary NSAID oral bolus for horses combining Nimesulide (400mg) + Paracetamol (1500mg). It relieves pain, fever, and inflammation caused by musculoskeletal disorders, febrile infections, traumatic injuries, and post-surgical conditions. Administered once daily orally at 1 bolus per 400–500 kg body weight for 3–5 days under veterinary supervision.
What Is Unizif Plus Bolus?
Unizif Plus Bolus is a trusted equine veterinary medication used to treat pain, inflammation, and fever in horses. It combines two clinically proven active ingredients — Nimesulide, a selective COX-2 inhibitor, and Paracetamol, a centrally acting antipyretic — to deliver dual-action therapeutic relief that single-agent NSAIDs often cannot match.
Recommended by equine veterinarians for musculoskeletal disorders, febrile infections, traumatic injuries, and post-surgical recovery, Unizif Plus Bolus is easy to administer once daily and is safe for working, racing, and performance horses at prescribed doses.
Composition of Unizif Plus Bolus
| Active Ingredient | Quantity (Approx.) | Therapeutic Function |
| Nimesulide | 400 mg | Anti-inflammatory, Analgesic — selective COX-2 inhibitor |
| Paracetamol | 1500 mg | Antipyretic, Analgesic — central action on hypothalamus |
Note: Always verify exact composition on the product label or with your veterinarian.
Why Vets Recommend Unizif Plus Bolus
- Dual-action formula — anti-inflammatory + antipyretic in a single bolus
- Fast relief — visible improvement typically within 24–48 hours
- Once-daily oral dosing — easy to administer in stable or field settings
- Selective COX-2 inhibition (Nimesulide) — lower gastrointestinal risk vs. traditional NSAIDs
- No sedation or performance disruption — safe for sport and working horses
- Cost-effective alternative to injectable NSAID therapies
When Is Unizif Plus Bolus Prescribed?
Dosage & Administration
Recommended dose: 1 bolus per 400–500 kg body weight, once daily (oral). Treatment duration: 3–5 days. Always administer under veterinary guidance.
| Horse Body Weight | Bolus Count | Frequency | Duration |
| 300–400 kg | 1 bolus | Once daily | 3–5 days |
| 401–500 kg | 1 bolus | Once daily | 3–5 days |
| 501–600 kg | 1.5 boluses | Once daily | 3–5 days |
| 601–700 kg | 2 boluses | Once daily | 3–5 days |
How to Administer
- Administer orally — by hand, dosing gun, or crushed into feed, molasses, or a palatable mash
- Ensure the horse consumes the entire dose
- Can be given with or without food — provide free access to fresh water throughout
- Observe for improvement within 24–48 hours
- Do not exceed the recommended dose unless explicitly advised by your veterinarian
| Condition Category | Examples |
| Musculoskeletal Disorders | Arthritis, osteoarthritis, joint stiffness, lameness, tendonitis, bursitis, laminitis |
| Febrile & Infectious Conditions | Equine influenza, respiratory infections, pneumonia, bronchitis, post-infectious fever, strangles |
| Traumatic Injuries | Wounds, soft tissue injuries, bruises, hoof abscess pain |
| Post-Surgical Pain | Castration, dental surgery, orthopedic interventions |
| Gastrointestinal Discomfort | Mild colic (supportive care, as part of multimodal therapy) |
| General Acute Pain | Any short-term pain requiring fast relief during recovery or rehabilitation |
Safety, Precautions & Contraindications
⚠ Important Safety Information
Always use Unizif Plus Bolus under the supervision of a licensed veterinarian. Do not self-prescribe or exceed the recommended dose.
- Ensure horses are well-hydrated throughout treatment — NSAIDs can affect renal function in dehydrated animals
- Limit use to 3–5 days; prolonged use increases risk of GI, renal, and hepatic side effects
- Do not combine with other NSAIDs (phenylbutazone, flunixin) or corticosteroids — significantly increases GI ulcer and kidney injury risk
- Use with caution in geriatric horses or those with known liver or kidney disorders
Contraindications — Do Not Use In:
- Horses with active gastric ulcers or a history of colic
- Pregnant or lactating mares (unless directed by veterinarian)
- Foals under 6 months of age
- Horses with known hypersensitivity to NSAIDs or paracetamol
Possible Side Effects
Most horses tolerate Unizif Plus well at recommended doses. Side effects are more likely with overdose, prolonged use, or use in compromised animals. Discontinue immediately and contact your veterinarian if you observe any of the following:
| System | Possible Side Effects |
| Gastrointestinal | Loss of appetite, colic, diarrhea, gastric ulcers |
| Renal (Kidneys) | Reduced urination, elevated creatinine levels |
| Hepatic (Liver) | Elevated liver enzymes, jaundice (rare) |
| Behavioural | Lethargy, irritability, unusual depression |
| General | Fever, swelling, or skin rash in hypersensitivity cases |
Product Details
| Product Name | Unizif Plus Bolus |
| Pack Size | 10 Bolus |
| Price Range | $16.50 – $72.50 |
| Species | Horses (large equines) |
| Route of Administration | Oral (by mouth) |
| Active Ingredients | Nimesulide 400mg + Paracetamol 1500mg |
| Prescription Required | Yes — veterinary prescription required |
| Delivery | Fast delivery across India — typically 3–5 business days |
| Platform | Sold exclusively on MomasPets (shop.momaspets.com) |
🐴 Not sure if Unizif Plus is right for your horse?
Book a quick online vet consultation with Dr. Dinesh Moliya at MomasPets.
Dr. Moliya holds B.V.SC & A.H and M.V.SC & A.H qualifications with 16+ years of equine and veterinary experience.
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Disclaimer: This product should be used only under the direction of a licensed veterinarian. Always verify dosage and composition on the product label. MomasPets does not replace professional veterinary advice.
Michael R. –
My horse had severe joint swelling after a training session. Vet prescribed Unizif Plus and the improvement within 48 hours was remarkable. Will definitely reorder.”
Sarah Lim –
Used this for my mare’s post-surgery recovery. Pain was clearly managed well and she was back on her feet faster than expected. Great product, fast shipping too.
Carlos M –
My horse developed a fever after an infection and the vet recommended this bolus. Temperature was back to normal within a day. Easy to administer and effective